The measurement and full statistical analysis including Bayesian methods of the aluminium content of infant vaccines

Aluminium salts are the most common adjuvants in infant vaccines. The aluminium content of a vaccine is provided by manufacturer and indicated on patient information leaflet. There no independent verification, for example European Medicines Agency, We have measured thirteen vaccines using microwave-assisted acid peroxide digestion followed transversely heated graphite furnace atomic absorption spectrometry. Our data compared with manufacturer’s full statistical analyses including Bayesian methods. found that only three contained amount manufacturer. Six statistically significant (P < 0.05) greater quantity while four lower quantity. range any single varied considerably, example, from 0.172 to 0.602 mg/vaccine Havrix. raised specific questions about significance identified areas extremely limited information. Since known toxin humans specifically neurotoxin, its should be accurate independently monitored ensure both efficacy safety.